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  Cannabidiol inhibits proliferation of breast cancer cells
Posted by: wikicannabis - 06-20-2015, 03:30 PM - Forum: Medical Marijuana Studies & Research Wiki - No Replies

Marijuana & Cancer: Cannabidiol inhibits proliferation of breast cancer cells

Sean D. McAllister, PhD, Scientist at California Pacific Medical Center Research Institute, et al., stated the following in their Aug. 2011 study titled "Pathways Mediating the Effects of Cannabidiol on the Reduction of Breast Cancer Cell Proliferation, Invasion, and Metastasis," published in Breast Cancer Research and Treatment journal:

Quote:"There is a general consensus in the field of cancer research that targeting multiple pathways that control tumor progression is the best strategy for the eradication of aggressive cancers. Since CBD has a low toxicity, it would be an ideal candidate for use in combination treatments with additional drugs already used in the clinic. Importantly, CBD appears to be interacting through a cellular system that regulates the expression of key transcriptional factors (e.g., Id-1) that control breast cancer cell proliferation, migration, and invasion. The experiments described in this manuscript not only define the pathways that CBD is working through to control breast cancer cell aggressiveness, but also demonstrate the efficacy of CBD in pre-clinical models. A greater understanding of this system may lead to future therapies for breast cancer patients, including the additional refinement of CBD analog synthesis."
Aug. 2011 - Sean D. McAllister, PhD

[Editor's Note: The CBD was acquired from the National Institute of Health through the National Institute of Drug Abuse. CBD was extracted from marijuana plants grown at the University of Mississippi.]

Source: http://medicalmarijuana.procon.org/view....884#cancer

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  Patients report more effective than conventional drugs
Posted by: wikicannabis - 06-20-2015, 03:27 PM - Forum: Medical Marijuana Studies & Research Wiki - No Replies

Patients with bipolar disorder report that marijuana is more effective than conventional drugs.

Lester Grinspoon, MD, Professor of Psychiatry at the Harvard Medical School, et al., wrote in an Apr.-June 1998 article titled "The Use of Cannabis as a Mood Stabilizer in Bipolar Disorder: Anecdotal Evidence and the Need for Clinical Research" in Journal of Psychoactive Drugs:

Quote:"The authors present case histories indicating that a number of patients find cannabis (marihuana) useful in the treatment of their bipolar disorder. Some used it to treat mania, depression, or both. They stated that it was more effective than conventional drugs, or helped relieve the side effects of those drugs. One woman found that cannabis curbed her manic rages; she and her husband have worked to make it legally available as a medicine. Others described the use of cannabis as a supplement to lithium (allowing reduced consumption) or for relief of lithium's side effects. Another case illustrates the fact that medical cannabis users are in danger of arrest, especially when children are encouraged to inform on parents by some drug prevention programs.

An analogy is drawn between the status of cannabis today and that of lithium in the early 1950s, when its effect on mania had been discovered but there were no controlled studies. In the case of cannabis, the law has made such studies almost impossible, and the only available evidence is anecdotal. The potential for cannabis as a treatment for bipolar disorder unfortunately can not be fully explored in the present social circumstances."
Apr.-June 1998 - Lester Grinspoon, MD

Source: http://medicalmarijuana.procon.org/view....84#bipolar

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  Significantly better neurocognitive performance
Posted by: wikicannabis - 06-20-2015, 04:02 AM - Forum: Medical Marijuana Studies & Research Wiki - No Replies

Bipolar patients who also had cannabis use disorder (CUD) had significantly better neurocognitive performance than those without CUD

Raphael J. Braga, MD, Assistant Professor of Psychiatry at Hofstra North Shore-LIJ School of Medicine, et al., stated the following in their May 2012 study titled "Cognitive and Clinical Outcomes Associated with Cannabis Use in Patients with Bipolar I Disorder," published in Psychiatry Research:

Quote:"The objective of the present study was to compare clinical and neurocognitive measures in individuals with bipolar disorder with a history of cannabis use disorder (CUD) versus those without a history of CUD...

Results from our analysis suggest that subjects with bipolar disorder and history of CUDs demonstrate significantly better neurocognitive performance, particularly on measures of attention, processing speed, and working memory...

These data could be interpreted to suggest that cannabis use may have a beneficial effect on cognitive functioning in patients with severe psychiatric disorders. However, it is also possible that these findings may be due to the requirement for a certain level of cognitive function and related social skills in the acquisition of illicit drugs."
May 2012 -Raphael J. Braga, MD
Source: http://medicalmarijuana.procon.org/view....84#bipolar

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  ALS patients report marijuana provided wide relief
Posted by: wikicannabis - 06-20-2015, 03:57 AM - Forum: Medical Marijuana Studies & Research Wiki - No Replies

ALS (Lou Gehrig's Disease)

ALS patients said marijuana provided appetite stimulation, aided sleep, relieved anxiety and depression, and provided muscle relaxation

Jacob Kaufman, MD, third year resident in the Department of Neurology at the University of Pennsylvania, et al., stated the following in their Apr. 29, 2014 study titled "Medical Marijuana Utilization and Perceived Therapeutic Value in Patients with ALS (P3.014)," published in Neurology:
"Cannabis has immunomodulatory [capable of regulating immune functions] properties and effects upon excitotoxicity [process by which neurons are damaged] that suggest that it might have a disease-modifying role in ALS [amyotrophic lateral sclerosis, aka Lou Gehrig's Disease]. There have also been some anecdotal reports suggesting that marijuana may be effective in alleviating certain ALS symptoms...

Quote:DESIGN/METHODS: We conducted an anonymous survey of all ALS patients attending the Penn ALS Center from June 2013 to the present...

RESULTS: The survey was given to 127 patients and 102 were completed (93% response rate). In total, 21% reported current or prior use of medical marijuana to treat their ALS symptoms. Of that 21%, large majorities considered it very effective in providing appetite stimulation (75%), aiding sleep (65%), relieving anxiety (80%), relieving depression (70%), and providing muscle relaxation (60%)...

CONCLUSIONS: Those of our patients currently using marijuana report a very significant treatment effect on many ALS symptoms."
Apr. 29, 2014 - Jacob Kaufman, MD


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Heart Welcome to WikiCannabis.com!
Posted by: wikicannabis - 06-18-2015, 08:00 PM - Forum: New WikiCannabis Member Intro - Replies (1)

Welcome to WikiCannabis.com! Thank you for visiting our new website for Cannabis Enthusiasts!

If you have already registered, thank you! Our New Member Intro center is a place for community members to introduce themselves and tell us whatever you want about you and your love for cannabis!

Everyone is welcome and nothing but love to each and all!

About WikiCannabis.com

WikiCannabis.com is a community-based cannabis information exchange for marijuana enthusiasts, activists, patients, backyard gardeners, master growers, and anyone else with an interest in compassion, basic rights, and FREEDOM!

Due to the Federal Prohibition on Cannabis combined with the fast changing but inconsistent state laws, information and research on marijuana has been stifled. And while there are still an abundance of data, research, and anecdotal evidence on not only the medical benefits of marijuana, but also on the cannabis plant's relative benign nature.

Doctors and even our President has come out and stated that marijuana, at worst, is no more dangerous than alcohol, with many agreeing that marijuana is the safer choice.


Our mission in launching WikiCannabis.com is to create a crowdsourced centralized cannabis information resource to share, inform, and educate about marijuana. 

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